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Efficacy and safety of dupilumab for the treatment of uncontrolled asthma: a meta-analysis of randomized clinical trials

机译：dupilumab治疗不受控制的哮喘的疗效和安全性：随机临床试验的荟萃分析

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摘要

BackgroundSeveral recent clinical trials have assessed the effects of dupilumab in uncontrolled asthma, but reached no definite conclusion. We therefore conducted this meta-analysis to evaluate the overall efficacy and safety of dupilumab for the treatment of uncontrolled asthma.

机译：背景最近的几项临床试验评估了dupilumab在不受控制的哮喘中的作用，但未得出明确的结论。因此，我们进行了这项荟萃分析，以评估dupilumab治疗不受控制的哮喘的整体疗效和安全性。

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期刊名称 Respiratory Research
作者
Xiao-feng Xiong; Min Zhu; Hong-xia Wu; Li-li Fan; De-yun Cheng;
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作者单位

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年(卷),期 2019(20),-1
年度 2019
页码 108
总页数 11
原文格式 PDF
正文语种
中图分类呼吸生理学;
关键词
Dupilumab Meta-analysis Randomized control trial Uncontrolled asthma;

机译：Dupilumab;Meta分析;随机对照试验;非对照哮喘;
入库时间 2022-08-17 12:47:26

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1. Dupilumab safety and efficacy in uncontrolled asthma: a systematic review and meta-analysis of randomized clinical trials [J] . Yazan Zayed, Babikir Kheiri, Momen Banifadel, The journal of asthma . 2019,第10期

机译：不受控制的哮喘的杜帕米布安全和疗效：随机临床试验的系统评价和荟萃分析
2. Efficacy and safety of dupilumab for the treatment of adult atopic dermatitis: A meta-analysis of randomized clinical trials [J] . Han Yue, Chen Yuxin, Liu Xiaochun, The Journal of Allergy and Clinical Immunology . 2017,第3期

机译：杜帕里姆人治疗成人特应性皮炎的疗效和安全性：随机临床试验的荟萃分析
3. Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting beta(2) agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial [J] . Wenzel Sally, Castro Mario, Corren Jonathan, The Lancet . 2016,第10039期

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4. High Dose Vitamin E Supplementation and Mortality: Discussion of the Results of a Meta-analysis of Randomized Controlled Clinical Trial [C] . International Society for Free Radical Research . 2006

机译：高剂量维生素E补充和死亡率：讨论随机对照临床试验的荟萃分析结果
5. Efficacy of the Chinese herbal formula CUF2 in the treatment of childhood asthma: Animal experiment, in vitro study and randomized, double-blinded, placebo-controlled clinical trial. [D] . Wong, Yeuk Oi. 2006

机译：中药配方CUF2在治疗儿童哮喘中的功效：动物实验，体外研究以及随机，双盲，安慰剂对照的临床试验。
6. Liberty Asthma QUEST: Phase 3 Randomized Double-Blind Placebo-Controlled Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled Moderate-to-Severe Asthma [O] . William W. Busse, Jorge F. Maspero, Klaus F. Rabe, -1

机译：自由性哮喘研究：3期随机双盲安慰剂对照平行组研究评估未控制中度至重度哮喘患者的Dupilumab疗效/安全性
7. Efficacy and safety of dupilumab for the treatment of uncontrolled asthma: a meta-analysis of randomized clinical trials [O] . Xiao-feng Xiong, Min Zhu, Hong-xia Wu, 2019

机译：杜帕里姆为治疗不受控制的哮喘的疗效和安全性：随机临床试验的META分析

Efficacy and safety of dupilumab for the treatment of uncontrolled asthma: a meta-analysis of randomized clinical trials

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