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Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro

机译:己酸17alpha-羟孕酮(17P)对体外人肌膜收缩力的功能作用

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摘要

Background17alpha-hydroxyprogesterone caproate (17P) administration reportedly improves outcome for women with a previous spontaneous preterm delivery. This study, using in vitro strips of human uterine smooth muscle, aimed to investigate the direct non-genomic effects of 17P on spontaneous and induced contractions in tissues obtained during pregnancy, and in the non-pregnant state.
机译:Background17alpha-hydroxyprogesterone caproate(17P)的使用据报道可改善先前自发早产的妇女的预后。这项研究使用人子宫平滑肌的体外条带,旨在研究17P对在怀孕期间和处于非怀孕状态下获得的自发性和诱发性收缩的直接非基因组效应。

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