The programs offer the possibility of comparing pairs of homologous sequences in order to find out percentage of homology, number of identical and deviating nucleotides, of transitions and transversions and, derived from these, KNUC-values according to Kimura (1) and the corresponding standard error sigmaK. The sequences can be printed in pairs underneath each other, homologies are indicated by asterisks between the identical nucleotides. Out of a set of homologous sequences stored on a disk any number of sequences can be compared in pairs in this way, and a matrix containing either the percentage of homology values, the number of deviating nucleotides or the KNUC-values together with the corresponding standard errors can be sent to screen, printer or disk. A program will be available soon which creates a dendrogram representing the similarity between the sequences by use of an average linkage clustering method deduced from this matrix. The programs are written for Apple II computers using UCSD-PASCAL and for Sirius I/Victor 9000 computers using TURBO-PASCAL.
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机译：该程序提供了比较成对的同源序列的可能性，以便找出同源性百分比，相同和不同核苷酸的数目，转变和转化以及从中得出的根据Kimura（1）和相应标准的KNUC值错误sigmaK。序列可以成对地彼此底下印刷，同源性由相同核苷酸之间的星号表示。在磁盘上存储的一组同源序列中，可以用这种方法成对比较任何数量的序列，并且矩阵中可以包含同源性值的百分比，偏离的核苷酸数或KNUC值以及相应的标准错误可以发送到屏幕，打印机或磁盘。一个程序将很快面世，该程序将使用从该矩阵推导的平均连锁聚类方法来创建表示序列之间相似性的树状图。这些程序是为使用UCSD-PASCAL的Apple II计算机和为TURBO-PASCAL的Sirius I / Victor 9000计算机编写的。
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