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Renal artery stenosis presenting with nephrotic-range proteinuria: a case report

机译:肾动脉狭窄伴肾病范围蛋白尿:一例报告

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摘要

Renal artery stenosis (RAS) is commonly presented with hypertension and chronic kidney disease. We report a rare case of RAS occurring in a 78-year-old man who presented with nephrotic-range proteinuria. Renal biopsy on the left side was performed, and results showed mesangiopathic glomerulonephritis, which was not compatible with the cause of nephrotic-range proteinuria. Proteinuria was decreased by angiotensin receptor blocker, but azotemia was aggravated. Therefore, angiotensin receptor blocker was discontinued inevitably and thorough evaluation for the possibility of RAS was performed. Computed tomography angiography revealed significant RAS on the left side and a renal artery stent was inserted. After stenting, aortic dissection developed and progressed despite tight control of blood pressure. After inserting another stent graft through the true lumen of the left renal artery, the patient's renal function and proteinuria improved markedly.
机译:肾动脉狭窄(RAS)通常伴有高血压和慢性肾脏疾病。我们报道了一个罕见的病例,该病例发生在一个患有肾病范围蛋白尿的78岁男性中。进行了左侧的肾脏活检,结果显示为中肾病性肾小球肾炎,与肾病范围蛋白尿的病因不相容。蛋白尿被血管紧张素受体阻滞剂减少,但氮质血症加剧。因此,不可避免地停用了血管紧张素受体阻滞剂,并对RAS的可能性进行了彻底的评估。计算机断层扫描血管造影显示左侧有明显的RAS,并插入了肾动脉支架。支架置入后,尽管严格控制了血压,但主动脉夹层仍在发展。通过左肾动脉真腔插入另一支支架移植物后,患者的肾功能和蛋白尿明显改善。

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