P08.29 Histologic study of microcirculation patterns in human glioblastoma

摘要

Introduction:Glioblastoma is one of the most angiogenic human tumors and characterized by microvascular proliferations. A better understanding of glioblastoma vasculature is needed to optimize anti-angiogenic therapy that has shown a promising but incomplet efficacy. Vasculogenic mimicry (VM) is known as non-endothelial tumor cell-lined microvascular channels in aggressive tumors, which may function as blood supply networks.