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More of an Art than a Science: Using Microbial DNA Sequences to Compose Music

机译:艺术而非科学:使用微生物DNA序列来创作音乐

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摘要

Bacteria are everywhere. Microbial ecology is emerging as a critical field for understanding the relationships between these ubiquitous bacterial communities, the environment, and human health. Next generation DNA sequencing technology provides us a powerful tool to indirectly observe the communities by sequencing and analyzing all of the bacterial DNA present in an environment. The results of the DNA sequencing experiments can generate gigabytes to terabytes of information, however, making it difficult for the citizen scientist to grasp and the educator to convey this data. Here, we present a method for interpreting massive amounts of microbial ecology data as musical performances, easily generated on any computer and using only commonly available or freely available software and the ‘Microbial Bebop’ algorithm. Using this approach, citizen scientists and biology educators can sonify complex data in a fun and interactive format, making it easier to communicate both the importance and the excitement of exploring the planet earth’s largest ecosystem.
机译:细菌无处不在。微生物生态学正在成为理解这些无处不在的细菌群落,环境与人类健康之间关系的关键领域。下一代DNA测序技术为我们提供了强大的工具,可通过对环境中存在的所有细菌DNA进行测序和分析来间接观察群落。 DNA测序实验的结果可以生成千兆字节到TB级的信息,但是,这使得公民科学家难以掌握,教育者也难以传达这些数据。在这里,我们介绍了一种方法,可将大量微生物生态学数据解释为音乐表演,可在任何计算机上轻松生成,并且仅使用普遍可用或免费提供的软件以及“微生物比博普”算法即可。使用这种方法,公民科学家和生物学教育者可以以有趣且互动的格式对复杂的数据进行超声处理,从而更易于传达探索地球上最大的生态系统的重要性和兴奋性。

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