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A Single-Center Retrospective Study of Acute Kidney Injury Incidence in Patients With Advanced Malignancies Treated With Antimitochondrial Targeted Drug

机译：抗线粒体靶向药物治疗晚期恶性肿瘤急性肾脏损伤发生率的单中心回顾性研究

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IntroductionMitochondrial dysfunction plays an important role in the pathophysiology of kidney disease. Inhibitors of mitochondrial metabolism are being developed for the treatment of solid organ and hematologic malignancies. We describe the incidence and clinical features of acute kidney injury (AKI) in patients treated with the antimitochondrial drug CPI-613.

机译：简介线粒体功能障碍在肾脏疾病的病理生理中起着重要作用。线粒体代谢的抑制剂正在开发中，用于治疗实体器官和血液系统恶性肿瘤。我们描述了用抗线粒体药物CPI-613治疗的患者的急性肾损伤（AKI）的发生率和临床特征。

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期刊名称 Kidney International Reports
作者
Elizabeth M. Anderson; Jin Zhang; Greg Russell; Isai G. Bowline; Braghadheeswar Thyagarajan; DengFeng Li; Lijun Ma; Erica R. Anderson; Mariana Murea;
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作者单位

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年(卷),期 2019(4),2
年度 2019
页码 310–320
总页数 11
原文格式 PDF
正文语种
中图分类泌尿科学（泌尿生殖系疾病）;小儿泌尿科学;肾疾病;
关键词
acute kidney injury antimitochondrial therapy chemotherapy CPI-613 mitochondria;

机译：急性肾脏损伤;抗线粒体疗法;化学疗法;CPI-613;线粒体;

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专利

1. A Single-Center Retrospective Study of?Acute Kidney Injury Incidence in Patients With Advanced Malignancies Treated With?Antimitochondrial Targeted Drug [J] . Elizabeth M. Anderson, Jin Zhang, Greg Russell, Kidney International Reports . 2019,第2期

机译：抗线粒体靶向药物治疗晚期恶性肿瘤急性肾脏损伤发生率的单中心回顾性研究
2. A Single-Center Retrospective Study of?Acute Kidney Injury Incidence in Patients With Advanced Malignancies Treated With?Antimitochondrial Targeted Drug [J] . Elizabeth M. Anderson, Jin Zhang, Greg Russell, Kidney International Reports . 2019,第2期

机译：抗线粒体靶向药物治疗晚期恶性肿瘤急性肾脏损伤发生率的单中心回顾性研究
3. Higher incidence of acute kidney injury in patients treated with piperacillin/tazobactam than in patients treated with cefepime: a single-center retrospective cohort study [J] . Shota Kadomura, Yoh Takekuma, Yuki Sato, Journal of Pharmaceutical Health Care and Sciences . 2019,第1期

机译：用Piperacillin / Tazobactam治疗的患者急性肾损伤的发病率高于用头脑治疗的患者：单中心回顾性队列研究
4. Incidence and Clinical Features of Acute Lung Injury/ Adult Respiratory Distress Syndrome Complicating Acute Myocardial Infarction Patients Treated with Primary Angioplasty [C] . Garcia Gonzalez M.J., Juarez Prera R., Blanco Palacios G., International Congress on Coronary Artery Disease . 2009

机译：急性肺损伤/成人呼吸窘迫综合征复杂性急性心肌梗死患者的发病率和临床特征对初级血管成形术治疗的急性心肌梗死患者
5. The incidence and consequences of acute kidney injury in kidney transplant recipients. [D] . Mehrotra, Anita. 2010

机译：肾移植受者急性肾损伤的发生率和后果。
6. Higher incidence of acute kidney injury in patients treated with piperacillin/tazobactam than in patients treated with cefepime: a single-center retrospective cohort study [O] . Shota Kadomura, Yoh Takekuma, Yuki Sato, 2019

机译：哌拉西林/他唑巴坦治疗的患者急性肾损伤的发生率比头孢吡肟治疗的患者高：单中心回顾性队列研究
7. A Single-Center Retrospective Study of Acute Kidney Injury Incidence in Patients With Advanced Malignancies Treated With Antimitochondrial Targeted Drug [O] . Elizabeth M. Anderson, Jin Zhang, Greg Russell, 2019

机译：用抗度靶向药物治疗晚期恶性肿瘤患者急性肾损伤发病率的单中心回顾性研究

A Single-Center Retrospective Study of Acute Kidney Injury Incidence in Patients With Advanced Malignancies Treated With Antimitochondrial Targeted Drug

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