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Carotid artery stenting vs. carotid endarterectomy in the management of carotid artery stenosis: Lessons learned from randomized controlled trials

机译:颈动脉狭窄与颈动脉内膜切除术治疗颈动脉狭窄:从随机对照试验中学到的经验教训

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摘要

Background:Carotid artery stenosis, both symptomatic and asymptomatic, has been well studied with several multicenter randomized trials. The superiority of carotid endarterectomy (CEA) to medical therapy alone in both symptomatic and asymptomatic carotid artery stenosis has been well established in previous trials in the 1990s. The consequent era of endovascular carotid artery stenting (CAS) has offered another option for treating carotid artery stenosis. A series of randomized trials have now been conducted to compare CEA and CAS in the treatment of carotid artery disease. The large number of similar trials has created some confusion due to inconsistent results. Here, the authors review the trials that compare CEA and CAS in the management of carotid artery stenosis.
机译:背景:有症状和无症状的颈动脉狭窄已通过多项多中心随机试验得到了很好的研究。在有症状和无症状的颈动脉狭窄中,颈动脉内膜切除术(CEA)优于仅药物治疗的优势在1990年代的先前试验中已经得到了很好的证实。随之而来的血管内颈动脉支架置入术(CAS)时代为治疗颈动脉狭窄提供了另一种选择。现在已经进行了一系列随机试验,以比较CEA和CAS在颈动脉疾病的治疗中的作用。由于结果不一致,大量类似的试验造成了一些混乱。在这里,作者回顾了比较CEA和CAS在颈动脉狭窄治疗中的试验。

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