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Effects of low-dose ketamine infusion on remifentanil-induced acute opioid tolerance and the inflammatory response in patients undergoing orthognathic surgery

机译：小剂量氯胺酮输注对瑞芬太尼诱导的急性阿片样物质耐受性和正颌手术患者的炎症反应的影响

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摘要

PurposeRemifentanil is associated with acute opioid tolerance that can lead to increased postoperative consumption of opioid analgesics. The purpose of this study was to determine whether a low dose of ketamine prevents remifentanil-induced acute opioid tolerance and affects the neutrophil–lymphocyte ratio (NLR), a newly recognized biomarker of inflammation.

机译：目的瑞芬太尼与急性阿片类药物耐受性相关，可导致术后阿片类镇痛药的消费增加。这项研究的目的是确定低剂量的氯胺酮是否可以预防瑞芬太尼诱导的急性阿片样物质耐受性，并影响新近公认的炎症生物标记物嗜中性白细胞-淋巴细胞比率（NLR）。

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期刊名称 Journal of Pain Research
作者
Kanta Kido; Shinichi Toda; Yuki Shindo; Hitoshi Miyashita; Shigekazu Sugino; Eiji Masaki;
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作者单位

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年(卷),期 2019(12),-1
年度 2019
页码 377–385
总页数 9
原文格式 PDF
正文语种
中图分类基础医学;
关键词
acute tolerance central sensitization NMDA receptor neutrophil–lymphocyte ratio remifentanil;

机译：急性耐受;中枢敏化;NMDA受体;中性粒细胞-淋巴细胞比;瑞芬太尼;

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机译：非透析慢性肾病患者接受冠状动脉旁路移植术的低剂量人心钠素输注结果：NU-HIT（日本大学工作组在心脏外科手术期间进行低剂量HANP输注疗法研究）的CKD试验。
2. Perioperative very low-dose ketamine infusion actually increases the incidence of postoperative remifentanil-induced shivering-double-blind randomized trial [J] . Manzo Suzuki, Makoto Osumi, Hiromi Shimada, Acta anaesthesiologica Taiwanica : . 2013,第4期

机译：围术期非常低剂量的氯胺酮输注实际上增加了瑞芬太尼诱发的寒战-双盲随机试验的发生率
3. Low-Dose Ketamine Infusions for Highly Opioid-Tolerant Adults Following Spinal Surgery: A Retrospective Before-and-after Study [J] . Vaid Patrycja, Green Theresa, Shinkaruk Kelly, Pain management nursing: official journal of the American Society of Pain Management Nurses . 2016,第2期

机译：小剂量氯胺酮输注高度耐受阿片类药物的成年人脊柱手术后：回顾性的前后研究。
4. Intraoperative Radlomaze for Atrial Fibrillation Patients Undergoing Heart Surgery: Which Acute and Long Term iesults? [C] . A. Venturini, A. Asta, D. Manging, International Workshop on Cardiac Arrhythmias . 2002

机译：心房颤动患者进行心房手术的术中辐射：哪种急性和长期的IESults？
5. Effects of estrogen and progesterone on acute nociception responses and the development of opioid tolerance. [D] . Kemen, Lynne M. 2005

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6. Effects of Low-Dose Ketamine Infusion on Alleviating the Opioid Burden for Patients Undergoing Myomectomy Surgery [O] . Amr Samir Wahdan, Mennattah Magdi Mohamed, Nadia Youssef Helmy, 2021

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7. The Effects of Intraoperative Adenosine Infusion on Acute Opioid Tolerance and Opioid Induced Hyperalgesia Induced by Remifentanil in Adult Patients Undergoing Tonsillectomy [O] . Lee, Cheol, Song, Yoon Kwang, Lee, Ju Hwan, 2011

机译：术中腺苷输注对瑞芬太尼对扁桃体切除术后成年患者急性阿片耐受性和阿片类药物引起的痛觉过敏的影响
8. Effects of Perioperative Low Dose Ketamine Infusion on Postoperative Pain Perception in Males and Females Undergoing Laparoscopic Surgery [R] . Conroy, J. P. , Cusick, W. T. 2003

机译：围手术期低剂量氯胺酮输注对男性和女性腹腔镜手术术后疼痛感知的影响

Effects of low-dose ketamine infusion on remifentanil-induced acute opioid tolerance and the inflammatory response in patients undergoing orthognathic surgery

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