Long-term impact of liraglutide a glucagon-like peptide-1 (GLP-1) analogue on body weight and glycemic control in Japanese type 2 diabetes: an observational study

摘要

BackgroundLiraglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been shown to possess pleiotropic effects including body weight reduction. However, long-term effect of liraglutide on body weight and glycemic control has not been elucidated in Japanese type 2 diabetes (T2D) subjects. Present study investigates whether liraglutide treatment maintains the body weight-decreasing and glucose-lowering effects for 2 years in Japanese T2D subjects.