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Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation

机译：蒙特卡罗模拟分析脑室外侧引流后脑出血患者血浆/脑脊液中利奈唑胺的药代动力学和药效学

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ObjectiveWe investigated the pharmacokinetic (PK) and pharmacodynamic (PD) parameters of linezolid in patients who had suffered cerebral hemorrhage after lateral ventricular drainage.

机译：目的研究利奈唑胺在侧脑室引流后脑出血患者中的药代动力学（PK）和药效动力学（PD）参数。

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期刊名称 Drug Design Development and Therapy
作者
Xiaofei Wu; Yan Tang; Xiaohua Zhang; Chenchen Wu; Lingti Kong;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 1679–1684
总页数 6
原文格式 PDF
正文语种
中图分类药学 ; 药物化学 ;
关键词
linezolid cerebral hemorrhage plasma cerebrospinal fluid pharmacokinetics pharmacodynamics Monte Carlo simulation;

机译：利奈唑胺;脑出血;血浆;脑脊髓液;药代动力学;药效学;蒙特卡洛模拟;

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专利

1. Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation [J] . Xiaofei Wu, Yan Tang, Xiaohua Zhang, Drug Design, Development and Therapy . 2018 ,第4期

机译：蒙特卡罗模拟分析脑室外侧引流后脑出血患者血浆/脑脊液中利奈唑胺的药代动力学和药效学
2. Pharmacokinetics of linezolid in plasma and cerebrospinal fluid in patients with cerebral hemorrhage post-surgical intervention [J] . Tang Yan, Kong Lingti, Wu Chenchen, European journal of clinical pharmacology . 2017 ,第7期

机译：脑出血后手术干预患者血浆和脑脊髓液中线虫药的药代动力学
3. Pharmacokinetic/Pharmacodynamic Analysis of Meropenem for the Treatment of Nosocomial Pneumonia in Intracerebral Hemorrhage Patients by Monte Carlo Simulation [J] . Lingti Kong, Yan Tang, Xiaohua Zhang, The annals of pharmacotherapy . 2017 ,第11期

机译：Monte Carlo仿真治疗脑出血患者医院肺癌治疗医院肺炎的药代动力学/药效学分析
4. Proteomic analysis of cerebrospinal fluid and plasma in patients with Amyotrophic Lateral Sclerosis [C] . T. Nash, J. Beri, M. Bereman Annual conference of the International Society of Exposure Science . 2017

机译：肌萎缩性侧索硬化症患者脑脊液和血浆的蛋白质组学分析
5. Cerebrospinal fluid calcium, apoE protein and genotype in individuals with and without cerebral vasospasm after subarachnoid hemorrhage. [D] . Alexander, Sheila Ann. 2004

机译：蛛网膜下腔出血后有和没有脑血管痉挛的个体的脑脊液钙，apoE蛋白和基因型。
6. Optimizing the dosing regimen of linezolid in critically ill septic patients undergoing continuous hemodiafiltration using a pharmacokinetic/pharmacodynamic analysis and monte carlo simulation [O] . H Barrasa González, A Martín López, A Isla Ruiz, 2015

机译：使用药代动力学/药效学分析和蒙特卡洛模拟优化连续性血液透析滤过的危重脓毒症患者利奈唑胺的给药方案
7. OPTIMIZING THE DOSING REGIMEN OF LINEZOLID IN CRITICALLY ILL SEPTIC PATIENTS UNDERGOING CONTINUOUS HEMODIAFILTRATION USING A PHARMACOKINETIC/PHARMACODYNAMIC ANALYSIS AND MONTE CARLO SIMULATION [O] . H Barrasa González, A Martín López, A Isla Ruiz, 2015

机译：应用药动学/药代动力学分析和蒙特卡罗模拟优化连续性血液滤过的危重病患者的利奈唑类药物剂量方案

Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation

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