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First report of a phylogenetic analysis of an autochthonous Plasmodium vivax strain isolated from a malaria case in East Attica Greece

机译:希腊东阿提卡的疟疾病例中分离出的间质间日疟原虫菌株的系统发育分析的首次报告

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摘要

Malaria has become an emerging infection in Greece, which is the doorstep to Europe for thousands of immigrants. With increasing immigration, cases with evidence of domestic transmission (autochthonous) are being reported. In the present study, an isolate of Plasmodium vivax from an autochthonous clinical case was subjected to phylogenetic analysis of the genes encoding the merozoite surface protein 1 (MSP-1) and the circumsporozoite protein (CSP). In the MSP region, the strain was related with strains from Brazil, South Korea, Turkey and Thailand, whereas in the CSP region, with strains from Brazil, Colombia and New Guinea. The present study establishes for the first time in Greece the basis for the creation of a database comprising genotypic and phylogenetic characteristics of Plasmodium spp.
机译:疟疾已成为希腊的新兴感染,这是成千上万移民进入欧洲的大门。随着移民的增加,正在报告有家庭传播(自发)证据的病例。在本研究中,对来自本地临床病例的间日疟原虫分离株进行了系统发育分析,该基因编码裂殖子表面蛋白1(MSP-1)和环子孢子蛋白(CSP)。在MSP地区,该菌株与来自巴西,韩国,土耳其和泰国的菌株有关,而在CSP地区,与巴西,哥伦比亚和新几内亚的菌株有关。本研究首次在希腊建立了包括疟原虫属物种的基因型和系统发育特征的数据库的基础。

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