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Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat

机译：高脂和高胆固醇饮食引起的脂肪性肝炎和严重纤维化的同时变化新型SHRSP5 / Dmcr大鼠中的潜在分子机制

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摘要

ObjectivesThe aim of this study was to identify the molecular mechanisms underlying high-fat and high-cholesterol (HFC) diet-induced steatohepatitis and associated liver fibrosis progression in a novel stroke-prone, spontaneously hypertensive 5/Dmcr (SHRSP5/Dmcr) rat model.

机译：目的本研究的目的是在新型易发中风，自发性高血压5 / Dmcr（SHRSP5 / Dmcr）大鼠模型中确定高脂和高胆固醇（HFC）饮食诱导的脂肪性肝炎及相关肝纤维化进展的分子机制。

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期刊名称 Environmental Health and Preventive Medicine
作者
Takashi Moriya; Kazuya Kitamori; Hisao Naito; Yukie Yanagiba; Yuki Ito; Nozomi Yamagishi; Hazuki Tamada; Xiaofang Jia; Satoru Tsuchikura; Katsumi Ikeda; Yukio Yamori; Tamie Nakajima;
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作者单位

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年(卷),期 2012(17),6
年度 2012
页码 444–456
总页数 13
原文格式 PDF
正文语种
中图分类公共卫生工程;
关键词
Steatohepatitis Inflammation TNF-α NF-κb Fibrosis;

机译：脂肪性肝炎;炎症;TNF-α;NF-κb;纤维化;

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专利

1. Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat [J] . Takashi Moriya, Kazuya Kitamori, Hisao Naito, Environmental Health and Preventive Medicine . 2012,第6期

机译：高脂高胆固醇饮食诱导的脂肪性肝炎和严重纤维化的同时变化及其潜在分子机制在新型SHRSP5 / Dmcr大鼠中
2. Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat [J] . Takashi Moriya, Kazuya Kitamori, Hisao Naito, Environmental health and preventive medicine . 2012,第6期

机译：高脂高胆固醇饮食诱导的脂肪性肝炎和严重纤维化的同时变化及其潜在分子机制在新型SHRSP5 / Dmcr大鼠中
3. Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr [J] . Kazuya Kitamori, Hisao Naito, Hazuki Tamada, Environmental Health and Preventive Medicine . 2012,第3期

机译：高脂和高胆固醇饮食诱导的脂肪性肝炎和SHRSP5 / Dmcr严重纤维化进展的新型大鼠模型的建立
4. Molecular mechanisms of fibrosis progression in non-alcoholic steatohepatitis (NASH) [C] . C. HELLERBRAND Falk Symposium . 2008

机译：非酒精性脱脂性纤维化进展的分子机制（纳什）
5. Molecular Mechanisms Underlying microRNA-122 Mediated Suppression of Liver Inflammation, Fibrosis, and Carcinogenesis [D] . Teng, Kun-Yu. 2017

机译：MicroRNA-122介导的肝脏炎症，纤维化和致癌作用的分子机制
6. Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr [O] . Kazuya Kitamori, Hisao Naito, Hazuki Tamada, 2012

机译：高脂和高胆固醇饮食诱导的脂肪性肝炎和SHRSP5 / Dmcr严重纤维化进展的新型大鼠模型的建立
7. Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr [O] . Kazuya Kitamori, Hisao Naito, Hazuki Tamada, 2011

机译：高脂肪和高胆固醇饮食诱导的ShRSP5 / DMCR中的高脂肪和高胆固醇饮食诱导的胫骨肝炎和严重纤维化进展的发展

Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat

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