Electroacupuncture stimulation (EAS) has been demonstrated effective for pain relief and treating other various diseases. However, the conventional way of EAS, the bi-acupoint method, is not suitable for basis study of acupoint specificity. Moreover, its operations are inconvenient and difficult to be persevered, especially for long-term, continuous and even imperative treatments. These disadvantages motivate designs of new EAS methods. We present a novel uni-acupoint electrical stimulation method, which is applied at a single acupoint and quite meets the needs of basis study and simpler clinical application. Its pain relief effect has been evaluated by animal tests of Wistar rats. During the experiments, rats were given 30 min 2/100 Hz uni- and bi-acupoint EAS and their nociceptive thresholds before and after EAS were attained by hot-plate test. The analgesic effect was defined as the change of nociceptive threshold and used to evaluate the effectiveness of uni-acupoint EAS for pain relief. The hot-plate test results indicated that analgesic effect of uni-acupoint group was significantly higher than that of the control group and there was no significant difference of analgesic effects between uni- and bi-acupoint EAS. The results suggested that uni-acupoint method was an effective EAS method and had comparable pain relief effect with bi-acupoint method.
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机译:已证明电针刺激(EAS)可有效缓解疼痛和治疗其他各种疾病。但是,传统的EAS方法,即双穴法,不适用于穴位特异性的基础研究。而且,其操作不便且难以坚持,特别是对于长期,连续甚至必要的治疗。这些缺点激发了新的EAS方法的设计。我们提出了一种新颖的单穴电刺激方法,该方法适用于单穴,完全可以满足基础研究和简化临床应用的需要。通过Wistar大鼠的动物实验评估了其止痛效果。在实验过程中,大鼠通过热板试验获得了30 min 2/100 Hz单穴和双穴EAS,并在EAS前后达到了伤害阈值。镇痛作用定义为伤害性阈值的变化,用于评估单穴EAS缓解疼痛的效果。热板试验结果表明,单穴组的镇痛作用明显高于对照组,单穴和双穴EAS镇痛作用无明显差异。结果表明,单穴法是一种有效的EAS方法,其止痛效果可与双穴法相媲美。
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