PurposeTissue clearing has been used in anatomy for the first time in Germany over a century ago. Neuronal tissue, like cortex, was investigated in mice using a water-based optical clearing method termed See Deep Brain (SeeDB). However, although the eye belongs to the central nervous system, this histological technique was not applied in the eye up to date. We applied SeeDB for the visualization of intraocular structures.
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机译:目的组织清理已在一个多世纪前首次在德国用于解剖学。使用称为See Deep Brain(SeeDB)的水基光学清除方法,对小鼠的神经元组织(如皮质)进行了研究。然而,尽管眼睛属于中枢神经系统,但这种组织学技术迄今尚未应用于眼睛。我们将SeeDB应用于眼内结构的可视化。
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