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Neurobehavioral Abnormalities Associated with Executive Dysfunction after Traumatic Brain Injury

机译:颅脑外伤后与执行功能障碍相关的神经行为异常

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摘要

>Objective: This article will address how anomalies of executive function after traumatic brain injury (TBI) can translate into altered social behavior that has an impact on a person’s capacity to live safely and independently in the community.>Method: Review of literature on executive and neurobehavioral function linked to cognitive ageing in neurologically healthy populations and late neurocognitive effects of serious TBI. Information was collated from internet searches involving MEDLINE, PubMed, PyscINFO and Google Scholar as well as the authors’ own catalogs.>Conclusions: The conventional distinction between cognitive and emotional-behavioral sequelae of TBI is shown to be superficial in the light of increasing evidence that executive skills are critical for integrating and appraising environmental events in terms of cognitive, emotional and social significance. This is undertaken through multiple fronto-subcortical pathways within which it is possible to identify a predominantly dorsolateral network that subserves executive control of attention and cognition (so-called cold executive processes) and orbito-frontal/ventro-medial pathways that underpin the hot executive skills that drive much of behavior in daily life. TBI frequently involves disruption to both sets of executive functions but research is increasingly demonstrating the role of hot executive deficits underpinning a wide range of neurobehavioral disorders that compromise relationships, functional independence and mental capacity in daily life.
机译:>目标:本文将探讨脑外伤(TBI)后执行功能的异常如何转化为改变的社会行为,从而影响一个人在社区中安全独立生活的能力。> >方法:综述与神经系统健康人群的认知老化和严重TBI的晚期神经认知作用有关的执行和神经行为功能。信息来自MEDLINE,PubMed,PyscINFO和Google Scholar的互联网搜索以及作者自己的目录。>结论:TBI的认知和情绪-行为后遗症之间的常规区别被证明是肤浅的鉴于越来越多的证据表明,执行技巧对于从认知,情感和社会意义上整合和评估环境事件至关重要。这是通过多种额皮质下途径进行的,在这些途径中,有可能识别出主要的背外侧网络,这些网络可为行政人员控制注意力和认知(所谓的冷行政人员流程)以及支持热行政人员的眶额/中枢途径提供支持。推动日常生活中许多行为的技能。 TBI经常涉及到这两种执行功能的破坏,但是研究越来越显示出执行力不足的热病是多种神经行为障碍的基础,这些神经病在日常生活中会损害人际关系,功能独立性和智力。

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