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Cornell Alliance for Science Evaluation of Consensus on Genetically Modified Food Safety: Weaknesses in Study Design

机译:康奈尔大学转基因食品安全共识科学评估联盟:研究设计的不足

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摘要

Cornell Alliance for Science has launched an initiative in which “citizen scientists” are called upon to evaluate studies on health risks of genetically modified (GM) crops and foods. The purpose is to establish whether the consensus on GM food safety claimed by the American Association for the Advancement of Science (AAAS) is supported by a review of the scientific literature. The Alliance’s citizen scientists are examining more than 12,000 publication abstracts to quantify how far the scientific literature supports the AAAS’s statement. We identify a number of fundamental weaknesses in the Alliance’s study design, including evaluation is based only on information provided in the publication abstract; there is a lack of clarity as to what material is included in the 12,000 study abstracts to be reviewed, since the number of appropriately designed investigations addressing GM food safety are few; there is uncertainty as to whether studies of toxic effects arising from GM crop-associated pesticides will be included; there is a lack of clarity regarding whether divergent yet equally valid interpretations of the same study will be taken into account; and there is no definition of the cutoff point for consensus or non-consensus on GM food safety. In addition, vital industry proprietary biosafety data on GM crops and associated pesticides are not publicly available and is thus cannot inform this project. Based on these weaknesses in the study design, we believe it is questionable as to whether any objective or meaningful conclusion can be drawn from the Alliance’s initiative.
机译:康奈尔科学联盟发起了一项倡议,其中呼吁“公民科学家”评估有关转基因作物和食品健康风险的研究。目的是确定对美国科学发展协会(AAAS)所宣称的有关转基因食品安全的共识是否得到对科学文献的评论的支持。该联盟的公民科学家正在研究12,000多种出版物摘要,以量化科学文献对AAAS声明的支持程度。我们发现了联盟研究设计中的一些基本弱点,包括评估仅基于出版物摘要中提供的信息;由于要针对转基因食品安全进行适当设计的调查的数量很少,因此对于要审查的12,000份研究摘要中包含哪些材料尚不清楚。关于是否将转基因作物相关农药产生的毒性影响的研究是否包括在内尚不确定;关于是否会考虑对同一研究的不同但同样有效的解释尚不明确;对于转基因食品安全,没有共识或不同意的临界点的定义。此外,关于转基因作物和相关农药的至关重要的行业专有生物安全数据尚未公开,因此无法为该项目提供信息。基于研究设计中的这些弱点,我们认为是否可以从联盟的倡议中得出任何客观或有意义的结论值得怀疑。

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