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An unusual diagnosis for persistent diarrhoea and vomiting

机译:持续性腹泻和呕吐的异常诊断

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摘要

Identifying the etiology of chronic diarrhoea might be challenging in some patients, and before a diagnosis is made these patients may spend a substantial length of time with unresolved symptoms leading to uncertainty and anxiety that is severely impairing their life quality. A 45-year-old female was referred by her general practitioner with a 5-year history of increasingly frequent episodes of cyclical diarrhoea, vomiting, abdominal pain and intermittent palpitations. Contrast CT Abdomen/Pelvis revealed a 36x33x46 mm mass in the aorto caval region of her retro-peritoneum, just above the bifurcation.  On the basis of her symptoms, CT findings and an elevated plasma metanephrine level of 2314pmol/L (normal range 80 – 510pmol/L), it was at this point a likely diagnosis of a phaeochromocytoma was made. The retroperitoneal mass was successfully resected, and the histology confirmed a Phaeochromocytoma. Her symptoms rapidly improved and she made a good recovery. This unusual case highlights some of the dilemmas that arise when investigating patients with chronic and recurrent diarrhoea and vomiting.
机译:在某些患者中,确定慢性腹泻的病因可能具有挑战性,在做出诊断之前,这些患者可能要花费相当长的时间才能解决无法解决的症状,从而导致不确定性和焦虑感,从而严重影响他们的生活质量。一位全科医生转诊了一名45岁女性,有5年的历史,其周期性腹泻,呕吐,腹痛和间歇性心pit发作频率越来越高。对比CT腹部/骨盆显示其腹膜后主动脉腔区域的质量为36x33x46 mm,正好位于分叉处。根据她的症状,CT表现和血浆中甲肾上腺素水平升高至2314pmol / L(正常范围80 – 510pmol / L),此时可以诊断为嗜铬细胞瘤。腹膜后肿块成功切除,组织学证实为嗜铬细胞瘤。她的症状迅速好转,康复得很好。这种不寻常的情况突出显示了在调查患有慢性和复发性腹泻和呕吐的患者时出现的一些难题。

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