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Scientific evaluation of some Ayurvedic preparations for correction of iron deficiency and anemia

机译:对一些阿育吠陀制剂纠正缺铁和贫血的科学评估

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摘要

A number of preparations are available in Ayurved for treatment of anemia and iron deficiency. This study was designed to evaluate efficacy of some of them. Six most commonly used Ayurvedic iron containing preparations (Navayasa Curna, Punarnavadi Mandura, Dhatri Lauha, Pradarantaka Lauha, Sarva-Juara-Hara Lauha and Vrihat Yakrdari Lauha) were given in a dose of 250 mg b.d. for 30 days to six groups of iron deficient anemic patients; each group consisting of 20 patients. A control group was given Allopathic preparation—Irex-12, (containing—ferrous fumarate, vitamin C, folic acid and vitamin B12); 1 capsule daily for 30 days for comparison. All hematological and iron parameters were determined before and after completion of treatment. The results showed that there was statistically significant rise (p<0.001) in all of them—Hb, PCV, TRBC, MCV, MCH, MCHC and plasma iron, percent saturation and plasma ferritin. Total iron binding capacity decreased significantly (p<0.001). The response of most of Ayurvedic preparations was better than Allopathic preparation and there was no side effect as observed with iron salts The Hb regeneration rate was 0.10 g/dl/day for Allopathic preparation; while it was above this value for all Ayurvedic preparations exceptPradarantaka Lauha which was least effective.Sarva-Juara-Hara Lauha was the drug of choice as Hb regeneration with it was highest 0.16 g/dl/day. Upon analysis of Ayurvedic drugs, these results were found to be consistent and correlated with iron content of the preparation.
机译:阿育吠陀提供了许多用于治疗贫血和铁缺乏症的制剂。本研究旨在评估其中一些药物的疗效。服用六种最常用的含阿育吠陀铁的制剂(Navayasa Curna,Punarnavadi Mandura,Dhatri Lauha,Pradarantaka Lauha,Sarva-Juara-Hara Lauha和Vrihat Yakrdari Lauha),剂量为250 mgb.d。对六组缺铁性贫血患者进行30天;每组20例患者。对照组接受同种疗法制剂Irex-12(含有富马酸亚铁,维生素C,叶酸和维生素B12);每天1粒胶囊,连续30天进行比较。在治疗完成之前和之后确定所有血液学和铁学参数。结果表明,血红蛋白,血红蛋白,血红蛋白,TRBC,MCV,MCH,MCHC和血浆铁,饱和度百分比和血浆铁蛋白均在统计学上有显着上升(p <0.001)。总铁结合能力显着降低(p <0.001)。大多数阿育吠陀制剂的反应均优于同种疗法制剂,并且如铁盐所观察到的,没有副作用。同种疗法制剂的Hb再生速率为0.10 g / dl / day。沙瓦-朱拉-哈拉·劳哈(Sarva-Juara-Hara Lauha)是Hb再生的首选药物,其最高0.16 g / dl /天,而所有阿育吠陀制剂均高于该值,但Pradarantaka Lauha效果最差。对阿育吠陀药物进行分析后,发现这些结果是一致的,并且与制剂中的铁含量相关。

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