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Iron-type montmorillonite preparation for the treatment of hyperphosphatemia and iron deficiency anemia and its preparation method

机译:铁型蒙脱土治疗高磷血症和缺铁性贫血的制剂及其制备方法

摘要

The present invention relates to an iron-type montmorillonite preparation for treating hyperphosphatemia and iron deficiency anemia and a method for preparing the same. The preparation contains iron-type montmorillonite as an active ingredient, and the iron-type montmorillonite (Fe-montmorillonite) is obtained by immersing or eluting a drug montmorillonite in a water-soluble iron salt solution. The present invention is a drug produced by adding or not adding a pharmaceutical additive to the active ingredient, and when administered via the gastrointestinal tract, the active ingredient binds to a phosphate in the patient's gastrointestinal tract. Then, an insoluble substance is generated and discharged from the body through the digestive tract. This lowers the phosphate in the body of patients with chronic renal failure and achieves the purpose of treating hyperphosphatemia. At the same time, iron-type montmorillonite dissociates excess iron ions that are not bound to phosphate, and is absorbed by the human body to replenish iron ions in the body to treat iron deficiency anemia in patients with chronic renal failure. Fulfill. The above preparation can also be used as a prophylactic agent for hyperphosphatemia and iron deficiency anemia in patients with chronic renal failure. [Selection figure] None
机译:本发明涉及用于治疗高磷酸盐血症和铁缺乏性贫血的铁型蒙脱土制剂及其制备方法。该制剂包含铁型蒙脱石作为有效成分,并且铁型蒙脱石(Fe-蒙脱石)是通过将药物蒙脱石浸入或洗脱在水溶性铁盐溶液中而获得的。本发明是通过向活性成分中添加或不添加药物添加剂而产生的药物,并且当通过胃肠道给药时,该活性成分与患者胃肠道中的磷酸盐结合。然后,产生不溶性物质并通过消化道从体内排出。这降低了患有慢性肾衰竭的患者体内的磷酸盐,并达到了治疗高磷酸盐血症的目的。同时,铁型蒙脱石分解未与磷酸盐结合的过量铁离子,并被人体吸收以补充体内的铁离子,从而治疗慢性肾功能衰竭患者的铁缺乏性贫血。履行。上述制剂也可用作慢性肾衰竭患者的高磷酸盐血症和铁缺乏性贫血的预防剂。 [选择图]无

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