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Traffic-Related Air Pollution and Child BMI—A Study of Prenatal Exposure to Nitrogen Oxides and Body Mass Index in Children at the Age of Four Years in Malmö Sweden

机译:与交通有关的空气污染和儿童BMI —瑞典马尔默市4岁儿童的产前暴露于氮氧化物和体重指数的研究

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摘要

Traffic-related air pollution could be a danger to the health of children. Earlier studies have linked prenatal exposure to an increased risk of a range of diseases and negative health outcomes, including overweight and obesity. Presently, a knowledge gap exists in investigating the risk of overweight and obesity among children exposed to lower levels of air pollution in utero. This study aimed to investigate the relationship between prenatal traffic-related air pollution (nitrogen dioxides (NOx) and traffic density) and childhood overweight and obesity in Malmö, Sweden. A cohort, based on attendance of a four-year check-up examination at Swedish Child Health Care (CHC) centers, and a parent-assessed questionnaire provided data on body-mass index adjusted for four-year-old children (ISO-BMI) as well as socioeconomic and health variables. We estimated exposure by using traffic density and levels of NOx at the maternal geocoded residential level. Analysis of 5815 children was performed using binary logistic regression models. This study showed no associations of increased risk for childhood overweight or obesity through to prenatal exposure to NOx in this low-exposure setting. We further suggest analysis of risks related to exposure levels ranging between the ones presented here and those proposed in previous literature.
机译:与交通有关的空气污染可能对儿童的健康构成威胁。早期的研究将产前暴露与一系列疾病和负面健康结果(包括超重和肥胖)的风险增加联系起来。目前,在调查子宫内空气污染水平较低的儿童中超重和肥胖的风险方面存在知识差距。这项研究旨在调查瑞典马尔默市产前交通相关的空气污染(二氧化氮(NOx)和交通密度)与儿童超重和肥胖之间的关系。基于瑞典儿童保健(CHC)中心进行的四年体检的一项队列研究以及一项父母评估的问卷,该数据提供了针对四岁儿童调整的身体质量指数的数据(ISO-BMI )以及社会经济和健康变量。我们通过使用孕妇地理编码的居民区的交通密度和NOx含量来估算暴露程度。使用二进制逻辑回归模型对5815名儿童进行了分析。这项研究表明,在这种低暴露环境下,通过产前暴露NOx可以增加儿童超重或肥胖风险的相关性。我们进一步建议对与暴露水平有关的风险进行分析,其范围介于此处介绍的风险和先前文献中提出的风险之间。

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