Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III multi-centre randomised double-blind placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate

摘要

Objectives:This double-blind trial evaluated the efficacy and safety of abatacept or infliximab vs placebo. The primary objective of this study was to evaluate the mean change from baseline in Disease Activity Score (based on erythrocyte sedimentation rates; DAS28 (ESR)) for the abatacept vs placebo groups at day 197.