Method for estimating the efficacy of treatment with an anti-CD20 agent in a patient with rheumatoid arthritis and in inadequate response to at least one biotherapy

摘要

The present invention relates to a method for estimating the effectiveness of treatment with an anti-CD20 agent in a patient with rheumatoid arthritis and who has been in inadequate response to at least one previous biotherapy, comprising analyzing a biological sample from said patient. for the expression of a set of biomarkers, the results of which make it possible to determine whether said agent is a treatment which will generate a beneficial response for said patient. The present invention also relates to a system for estimating the effectiveness of said treatment in said patient comprising means for measuring or receiving data, the level of expression of said biomarkers and means for processing these data configured to estimate said effectiveness. of said treatment in said patient.