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Case Report: Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism)

机译:病例报告:致命甘草糖(滥用甘草导致假性醛固酮过多症)

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摘要

A 47-year-old woman was admitted to the emergency department with a history of asthenia, periorbital and lower limbs oedema, associated with hypokalaemia and increased blood pressure levels. Metabolic and renal causes were initially investigated as thyroid disease, Cushing syndrome and tubulopathies were excluded during the first week of admission. However, further questioning of the patient, revealed that she had been consuming several sachets of raw liquorice lollies (ignored amount) obtained from a herbalist a month ago. Based on the history and clinical findings, liquorice poisoning was highly suspected; an apparent mineralocorticoid excess secondary to ingestion of liquorice. Afterwards, levels of aldosterone and plasma renin activity were measured and found low 3 weeks later; therefore, our clinical suspicion was established. During the patient's stay at the hospital, liquorice was stopped and potassium supplements were started. Subsequently, a week after, the patient fully recovered without any significant sequelae.
机译:一名47岁的妇女因有乏力,眼眶水肿和下肢水肿,低钾血症和血压升高的病史进入急诊室。最初由于甲状腺疾病调查了代谢和肾脏原因,入院后第一周排除了库欣综合征和肾小管病变。但是,进一步询问该患者后,发现她一个月前一直在服用几包从草药师处获得的原始甘草糖(忽略量)。根据病史和临床发现,极有可能怀疑甘草中毒。摄入甘草精后明显的盐皮质激素过量。此后,测量醛固酮和血浆肾素活性的水平,并在3周后发现其低水平。因此,建立了我们的临床怀疑。在患者住院期间,甘草停止服用,并开始补充钾。随后,一周后,患者完全康复,没有任何明显的后遗症。

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