目的 探讨门脉断流术联合脾脏切除术与双介入栓塞术治疗肝硬化门脉高压症疗效. 方法 选择2011年1月至2014年1月期间,在本院收治的100例肝硬化门脉高压患者.50例观察组患者中,采取门脉断流术与脾脏切除术合用;50例对照组患者中,采取双介入栓塞术.对患者手术前后的血细胞计数、肝功能情况、并发症、随访1年后再出血率及死亡率进行分析. 结果 与对照组患者相比,观察组患者在1年后的白细胞计数、血小板计数、白蛋白、凝血酶原活动度等方面对比分析后,差异有统计学意义(t=4.124、6.481、4.104、2.234,P<0.05).但是在红细胞计数、总胆红素、谷丙转氨酶方面对比分析后,差异无统计学意义(t=0.732、0.084、0.142,P>0.05).对两组患者再出血率对比分析后,差异有统计学意义(χ2=6.292,P<0.05),对两组患者的死亡率对比分析后,差异有统计学意义(χ2=5.523,P<0.05). 结论 对于肝硬化门脉高压症患者,若患者的肝脏储备能力较强时,应该先选择外科手术方式,其效果显著,预后良好,值得大力推广.%Objective To investigate the efficacy of liver cirrhosis and portal hypertension treated with portal devascularization combined with splenectomy and dual interventional embolization. Methods 100 cases of patients with acute inferior wall myocardial infarction were selected from Jan-uary 2011 to January 2014, divided into the observation group and control group. 50 cases in the observation group, take the portal devascularization com-bined with splenectomy, 50 cases in the control group taking dual embolization. Blood cell counts in patients before and after surgery, liver function, compli-cations, bleeding follow-up a year and mortality were analyzed. Results Compared with the control group, the white blood cell count in patients after 1 year, platelet count, albumin, prothrombin activity of patients in the observation group, the difference was statistically significan (P<0.05). But the red blood cell count, total bilirubin, alanine aminotransferase after analyzing comparative terms, the difference was not statistically significan (P>0.05). Rebleeding rate after comparative analysis, the difference was statistically significant (χ2=6.292, P<0.05) between the two groups, the mortality rate after a comparative analysis between the two groups, the difference was statistically significan (χ2=5.523, P<0.05). Conclusion For patients with cirrhosis and portal hy-pertension, if liver reserve capacity is adequate, the surgical methods should be first selected, for good prognosis.
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