社会-医学-心理模式对血吸虫性终末期肝病患者的治疗作用

摘要

Objective To observe the influence of social medical and psychological treatment on patients with end-stage liver disease of schistosomiasis. Methods 63 cases of patients with end-stage liver disease of schistosomiasis(including 5 deaths during follow-up)accepted social medical and psychological treatment and follow-up of 1 years,the clinical features were observed before and after treatment,MNA-SF score changes,SF-36 score and MELD-Na score. Results There was significant difference after treatment,serum albumin,serum sodium concentration,ascites and hepatic encephalopathy situation(P<0.05),the quality of life of patients with increased,but the incidence of malnutrition,MNA-SF score,MELD-Na score change had no significant difference(P>0.05).Conclusion Social medical and psychological treatment patterns can help delay the clinical symptoms,improve the quality of life,but the prognosis is helpless to improve disease.%目的：观察社会-医学-心理治疗模式对血吸虫性终末期肝病患者的影响。方法63例血吸虫性终末期肝病患者（其中5例随访期间死亡）接受社会-医学-心理治疗并随访1年，观察治疗前后的临床特征及MNA-SF评分、SF-36评分、MELD-Na评分变化。结果治疗后血白蛋白、血清钠浓度、腹水程度和肝性脑病病情均有明显改善（P<0.05），患者生活质量有所提高，但营养不良发生率、MNA-SF评分、MELD-Na评分差异无统计学意义。结论社会-医学-心理治疗模式有助于延缓患者临床症状、改善生活质量，但无助于改变疾病的预后。