目的：通过比较64排螺旋CT（MSCT）和二维超声心动图（Echo）测量的左心室功能指标，探讨MSCT评价左室功能的应用价值。方法入选拟诊冠心病的患者84例，运用MSCT进行回顾性心电门控屏气技术扫描、图像重建和后处理，测量左心室的舒张末容积（LVEDV）、收缩末容积（LVESV）、每搏输出量（LVSV）和射血分数（LVEF），用Echo再次测量上述指标；运用配对t检验、Pearson相关和Bland-Altman法分析，比较两组数据的差异、相关性和一致性。结果 MSCT测量的左室容积指标较Echo测量值大，而两种方法的LVEF测量值接近；两组结果的相关性较好；Bland-Altman法分析发现两种方法测量结果具有较好的一致性。结论在拟诊为冠心病的患者中，MSCT能够提供与Echo相比拟的左室功能信息，结合冠状动脉成像，MSCT将更具实用价值。%Objects Toevauate the left ventricular function with 64-MSCT and to compare these data obtained by second harmonic 2D Echo,to discussed its application value on the evaluation of left ventricular function. Methods The LV volumes,stroke volume(SV) and ejection fraction(LVEF)obtained by 64-MDCT with retrospectively cardiac switch control breathless technology,scanning image reconstruction and post-processing were used in patients referred for non-invasive coronary vessels evaluation,then these data were also obtained by second harmonic 2D Echo,the difference,correlation and consistency of two groups were compared with matching t test, Pearson’s correlation and Bland-Altman method. Results LV volumes of 64-MSCT measurement were larger than Echo,LVEF measured value of two Methods were close:LVEDV(134.54±17.23 vs. 127.32±18.06,P<0.01),LVESV(65.56±11.97 vs. 57.35±10.25, P<0.01),LVSV(73.20±16.79vs69.21±13.76,P=0.02),LVEF(52.44±6.06 vs. 53.20±6.15,P=0.076). A close correlation between Echo and 64-MSCT for these indice existed:LVEDV(r=0.83),LVESV(r=0.84),LVSV(r=0.73),LVEF(r=0.80), with statistically significance(P<0.01).The agreement of two results was excellent. Conclusion 64-MDCT can be used to assess left ventricular function with good reproducibility and acceptable correlation respect to Echo in patients with suspected coronary heart disease. The combination of non-invasive coronary artery imaging and assessment of global LV function might become a fast and conclusive cardiac work-up in the future.
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