cqvip:Objective: To examine the temporal relation between depression and cognitive i mpairment in old age. Design: Prospective, population based study with four year s of follow up. Setting: City of Leiden, the Netherlands. Participants: 500 peop le aged 85 years at recruitment Main outcome measures: Annual assessments of dep ressive symptoms (15 item geriatric depression scale), global cognitive function (mini mental state examination) , attention (Stroop test), processing speed ( letter digit coding test), and immediate and delayed recall (12 word learning te st). Results: At 85 years old, participantsdepressive symptoms and cognitive i mpairment were highly significantly correlated (P.0.05). Conclusion: Care giver s should be aware of the development of depressive symptoms when cognitive impai rment is present. However, the presence of depression only does not increase the risk of cognitive decline.
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