小儿肺结核合并乙肝病毒携带抗结核治疗分析

摘要

Objective: To study the effect of anti tuberculosis treatment of tuberculosis and hepatitis B virus in children. Methods:from March 2015 to April 2012 in our hospital received treatment of pediatric pulmonary tuberculosis combined with hepatitis B virus carrying 47 patients as the object of this study, the treatment and the short course chemotherapy, the treatment effect of the observation and analysis. Results: after treatment, 47 patients in this group were significantly improved, a total of 9 cases of adverse reactions occurred, 6 cases of patients with TBIL increased, 6 cases of patients with AST increased, but A/G indicators are normal levels. After the treatment, the liver function of the patients recovered to normal level, and all the indexes and functional changes of the patients were treated with the original plan.Conclusion:the phenomenon of liver function damage occurred in the intensive treatment, so in the first 2 months of treatment, should be closely monitored in patients with liver function changes, such as liver damage, it is forbidden to use R.Z treatment.%目的：研究分析小儿肺结核合并乙肝病毒携带抗结核治疗效果。方法：选取2012年4月至2015年3月期间合作医院接受治疗的小儿肺结核合并乙肝病毒携带47例患者作为本次研究对象，对其进行治疗以及短程的化疗，对其治疗效效果进行观察与分析。结果：通过治疗后，本组47例患者的病情均得到了明显的好转，共计出现9例不良反应，均在强化治疗期间发生，6例患者出现TBIL升高的现象，6例患者出现AST升高的现象，但A/G指标均为正常水平。治疗半月后，患者的肝功能均恢复正常水平，在密切观测患者的各项指标以及功能变化情况下，使用原本的方案的对其进行治疗后，均未1例患者出现功能异常的表现。结论：肝功能损害的现象均发生在强化治疗期间，因此在前2个月的治疗时，应密切监测患者的肝功能变化情况，如以出现肝损伤，则严禁使用R.Z治疗进行治疗。