炎琥宁与α-干扰素治疗小儿急性上呼吸道感染的疗效比较及对血清超敏C反应蛋白、白细胞介素6的影响分析

摘要

Objective: Comparative analysis of Yanhuning and alpha-interferon in the treatment of infantile acute upper respiratory tract infection and their effects on serum high-sensitivity C - reactive protein (HS-CRP) and Interleukin -6 (IL-6). Methods: 98 cases of children with acute upper respiratory tract infection were randomly divided into 49 in an observation group and 49 in the control group. Patients in the observation group were treated with Yanhuning and those in the control group were treated with alpha-interferon therapy.Results: the total effective rate of the observation group is 93.88% while that of the control group is 81.63%. The indexes of the serum hs-CRP 2 and IL-6 were lower in both groups (P < 0.05), but that of the observation group is much lower than the control group.Conclusions: the effect of Yanhuning in the treatment of infantile acute upper respiratory tract infection is much better than that of the alpha-interferon. Therefore, more clinical applications of the Yanhuning should be recommended.%目的 对比分析炎琥宁与α-干扰素治疗小儿急性上呼吸道感染的疗效及对血清超敏C反应蛋白(hs-CRP)和白细胞介素-6(IL-6)的影响.方法 将98例急性上呼吸道感染患儿随机分为观察组49例和对照组49例.观察组患儿行炎琥宁治疗,对照组患儿行α-干扰素治疗.结果 观察组患儿临床治疗的总有效率为93.88%,对照组为81.63%,2组比较,差异具有统计学意义(P<0.05).治疗后,2组患儿的血清hs-CRP、IL-6指标值较治疗前均下降(P<0.05),但观察组患儿各指标的下降幅度均大于对照组(P<0.05).结论 炎琥宁治疗小儿急性上呼吸道感染的疗效要优于α-干扰素,更值得临床推广应用.