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卵巢早衰中医用药规律的文献研究

     

摘要

Sixty one papers on TCM treating premature ovarian failure published from January 1984 to December 2012 that met the in-clusion criteria were selected .Analysis was made on the four smell and five flavors of the drugs , the dosage , and the meridian tropism so as to explore premature ovarian failure treatment and drug application laws .Among them, the drug most frequently appeared was Angeli-ca, followed by Rehmannia, dodder, epimedium, licorice, etc.;the maximum total application dosage went to rehmannia , followed by angelica, dodder, epimedium, yams, etc.;the tonic medicine occurrence accounted for 57.14%, and its 56.02%effective dose among the total dose was the most used drugs in the treatment of premature ovarian failure ;various types of drugs in the liver meridian was 23. 24%, followed by kidney , heart, spleen;drugs with the propert of warm accounted for 26.88%, followed by cold medicines , which was 22.58%;medicines with the flavor nature of sweet accounted for 40.54%of the total, followed by bitter, acrid, sour.Treatment for this disease shall tonifying yin and yang since the pathogenesis was always related to deficiency .%本文通过筛选1984年1月至2012年12月符合纳入标准的中医药治疗卵巢早衰文献61篇,对治疗卵巢早衰药物的四气五味、药量、归经等进行了整理分析,以探讨卵巢早衰的治疗及用药规律。其中,药物出现次数最多的为当归,其次为熟地黄、菟丝子、淫羊藿、甘草等;使用总剂量最多的为熟地黄,其次为当归、菟丝子、淫羊藿、山药等;补虚药的出现次数占到57.14%,有效使用剂量占总剂量的56.02%,是治疗卵巢早衰药物中使用最多的;各类药物中归肝经最多,占总药味的23.24%,其次为肾经、心经、脾经;性温的药物在四气中所占比例最多,为26.88%,其次为寒性药物,为22.58%;甘味最多,占总药味的40.54%,其次为苦、辛、酸。药物的归经性味,与本病病机多虚、治疗上以补益阴阳为主相对应。

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