心理治疗联合131I治疗对女性甲亢患者的焦虑和抑郁水平的影响

摘要

Objective:To investigate the effects of psychological intervention on the curative rate and the levels of anxiety and depression in female patients with hyperthyroidism receiving 131 I treatment.Methods:Four hundred and eighty patients were divided into intervention group (n=248)and control group(n=232).The patients of control group received 131I treatment on-ly,while those in the intervention group received psychological intervention before 131 I treatment.At 3 months after 131 I treat-ment,anxiety and depression were evaluated using Self-rating Anxiety Scale (SAS)and Self-rating Depression Scale (SDS).For the assessment of curative rate,FT3,FT4 and TSH levels were examined at 1,3,6 months after 131 I treatment.Results:The average scores of SAS and SDS in the intervention group were both significantly lower than those in the control group (P < 0.01).In addition,the curative rate in the intervention group was higher than that in the control group (P < 0.01).Conclusion:Psycho-logical intervention can attenuate the anxiety and depression levels,and improve the curative rate in female patients with hyper-thyrodism receiving 131 I treatment.%目的：探讨心理治疗联合131 I 治疗对女性甲状腺机能亢进（以下简称甲亢）患者的焦虑和抑郁水平以及疗效的影响。方法：将480例女性甲亢患者分为心理治疗组（单日患者，n＝248）和对照组（双日患者，n＝232）。对照组只给予131 I 治疗，心理治疗组则在131 I 治疗前实施心理治疗。在131 I 治疗后3个月时，采用焦虑自评量表（SAS）和抑郁自评量表（SDS）测评两组的焦虑和抑郁水平，并比较两组的治愈率差异。两组患者均在131 I 治疗后1、3、6个月时进行甲状腺激素 FT3、FT4和 TSH 检测。结果：心理治疗组的 SAS 和 SDS 平均得分均显著低于对照组，差异有统计学意义（P ＜0．01）。此外，心理治疗组的治愈率明显高于对照组，差异有统计学意义（P ＜0．01）。结论：心理治疗能改善131 I 治疗的女性甲亢患者的焦虑和抑郁水平，并提高其疗效。