Method of treating anxiety and depression with 1-phenyl-2(1H,3H)- indolone psycho-therapeutic agents

摘要

Certain substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)- indolones are highly potent gabaergic agents, valuable in the treatment of individuals suffering from schizophrenia or reversing the side effects of a previously or concurrently administered neuroleptic agent; or in the treatment of epilepsy. A wider class of substituted 1-phenyl-3- (aminoalkylidene)-2(1H,3H)-indolones, together with 1-phenyl-3-(2- pyrrolidinylidene)-2(1H,3H)-indolones, and homologs thereof, are valuable in the treatment of anxiety.