目的：探讨缬沙坦联合复方丹参滴丸对早期2型糖尿病肾病患者尿微量白蛋白的影响。方法：将早期2型糖尿病肾病患者72例根据随机数字表法分为对照组和观察组各36例，对照组单纯给予缬沙坦治疗，观察组给予缬沙坦与复方丹参滴丸联合治疗，比较2组患者治疗前后血脂，肾功能及尿微量白蛋白水平的变化情况。结果：2组患者治疗前血脂水平和尿微量白蛋白排泄率比较差异无统计学意义(P＞0.05)，但观察组治疗后的血脂水平及尿微量白蛋白排泄率明显低于对照组(P＜0.05)。结论：与单纯使用缬沙坦的治疗方法相比，缬沙坦联合复方丹参滴丸治疗早期2型糖尿病肾病，能显著降低患者的血脂和尿微量白蛋白水平。%Objective:To study the influence of valsartan combined with compound DanShen dripping pills on urinary microalbumin of the patients with early type 2 diabetic nephropathy. Methods: Seventy-two patients were randomized into the control group and the observation group according to random number table, the control group were given valsartan, the observation group the combination of valsartan and compound DanShen dripping pills, the changes of blood lipid, renal function and the level of urinary microalbumin were compared between both groups. Results: The difference between both groups had no statistical meaning in the level of blood lipid and urinary microalbumin excretion rate (P>0.05), while the observation group group was notably lower than the control group after treating in the level of blood lipid and urinary microalbumin excretion rate (P<0.05). Conclusion:Compared with valsartan only, the combination therapy of valsartan and compound DanShen dripping pills could significantly decrease the levels of blood lipid and urinary microalbumin of the patients with early type 2 diabetic nephropathy.
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