猕猴眼屈光生物学参数的检测

摘要

目的：观察人工繁育猕猴眼球的屈光生物学参数，为眼动物实验提供可靠的参考数据。方法采用电脑验光仪、IOL-Master、角膜超声测厚仪，对47只猕猴93眼的屈光度数、角膜曲率半径、眼轴长度、中央角膜厚度等屈光生物学参数进行测量。结果各年龄组猕猴眼中央角膜厚度比较无统计学差异（P>0.05）；眼轴长度在2.5岁以前随年龄的增长不断变长，2.5岁以后眼轴长度可能不再变化；0.5岁组角膜曲率半径最小，随年龄增长有变长趋势，1.5岁以后趋于稳定；等效球镜屈光度数越小，轴率比就越大，2.5岁~4.5岁期间轴率比维持在一个较稳定的范围。结论与人类相比，人工繁育猕猴眼中央角膜厚度更薄，眼轴长度更短，角膜曲率半径也更小，角膜曲率半径和眼轴长度的变化规律和人类接近，可作为理想的动物眼实验模型。%Objectivethe ocular refractive parameters in rhesus monkeys have?been?detected to provide the relevant parameters.MethodsThe 93 eye diopter number, corneal radius of curvature, eye axial length, the central corneal thickness of 47 the macaques monkeys have been measured through the machines including computer refractometer,IOL - Master, corneal ultrasonic thickness gauge.ResultsMonkey eyes central corneal thickness comparison among all age groups had no statistical difference(P> 0.05);Ocular axial length before the age of 2.5,with the growth of the age,2.5 years after ocular axial length may no longer change;Corneal radius of curvature minimum 0.5 years old group,along with the age growth change trend, stabilise after 1.5 years;Equivalent spherical mirrors the smaller number of diopter,axial ratio,the shaft rate,of year 2.5-4.5 is maintained at a relatively stable range.ConclusionThe artificial breeding rhesus monkey eyes central corneal thickness is thinner,shorter axial length,corneal radius of curvature is smaller,the changing rule of the corneal curvature radius and the ocular axial length is closed to humans, can be used as ideal animal experimental model.