抗菌肽在断奶仔猪饲粮中的应用效果研究

摘要

This test was designed to study the effects of antimicrobial peptides (AMPs) in pig production. 180 pigs (10.30±1.13) kg had been randomly divided into 3 groups,and each group 4 repeats,each repeat 15 pigs.The con-trol group was fed based diet,the experimental group were fed basic feeding food with 500 mg/kg AMPs-A and 300 mg/kg AMPs-B.Experiment lasted for 28 days.Results showed that:1)compared with control group,ADG re-spectively increase 5.66%(P>0.05),3.92%(P>0.05),3.85%(P>0.05) the day of 1~14,15~28,1~28 in AMPs-A. 2)AMPs-A dramatically significantly reduce BUN 14.55%(P<0.01). 3)compared with control group,the IgG of AMPs-A and AMPs-B had increased 2.07%(P<0.05) and 1.27%(P<0.05);the TP of AMPs-A and AMPs-B had increased 4.48%(P<0.05) and 4.03%(P<0.05);and AMPs-A significantly increased T lymphatic conversion rates 39.02%(P<0.05) in blood.4)AMPs-A respectively significantly increased DM,CP and EE absorption rate 2.62%(P<0.05),3.95%(P<0.05),3.70%(P<0.05).5)E. coli colony count in pig feces had decreased 5.53%(P<0.05) and 3.77%(P<0.05) in AMPs-A and AMPs-B.Lactobacillus in AMPs-A and AMPs-B has increased 4.94%(P<0.05) and 3.67%(P<0.05),and Bifidobacterium colony count of AMPs-A and AMPs-B had increased 5.61%(P<0.05) and 4.75%(P<0.05).Adding AMPs in daily diet can effectively improve pig growth performance,blood physiologi-cal and biochemical indicators feed digestion utilization and improve intestinal microbial balance.The test indi-cate that adding AMPs-A is better than AMPs-B.%为研究抗菌肽（AMPs）在仔猪生产中的应用效果，选取（10.30±1.13） kg大白仔猪180头，随机分为3组，每组4个重复，每个重复15头，对照组饲喂基础饲粮，试验组分别在基础饲粮中添加抗菌肽A（AMPs-A）500 mg/kg和抗菌肽B（AMPs-B）300 mg/kg ，试验期28 d。结果表明：1）AMPs-A组在试验1～14 d、15～28 d、1～28 d这3个时间阶段日增重比对照组分别提高5.66%（P>0.05）、3.92%（P>0.05）、3.85%（P>0.05）。2）AMPs-A组血清尿素氮水平比对照组降低14.55%（P<0.01）。3）与对照组相比，AMPs-A、AMPs-B血液中IgG分别提高2.07%（P<0.05）、1.27%（P<0.05），血清总蛋白水平分别提高4.48%（P<0.05）、4.03%（P<0.05），血液T淋巴细胞转化率AMPs-A组提高39.02%（P<0.05）。4）AMPs-A组干物质、粗蛋白质和粗脂肪消化率分别比对照组提高2.62%（P<0.05）、3.95%（P<0.05）、3.70%（P<0.05）。5）肠道中大肠杆菌数，AMPs-A、AMPs-B比对照组分别降低5.53%（P<0.05）、3.77%（P<0.05）；乳酸杆菌数，AMPs-A、AMPs-B比对照组分别提高4.94%（P<0.05）、3.67%（P<0.05）；双歧杆菌数，AMPs-A、AMPs-B比对照组分别提高5.61%（P<0.05）、4.75%（P<0.05）。综上所述，在仔猪饲粮中添加AMPs可以有效提高仔猪的生长性能、饲料养分消化利用率，改善血清生理生化指标水平、肠道微生物平衡。综合本试验各项指标，仔猪饲粮中添加AMPs-A效果较好。