Objective This study was designed to compare the clinical characteristics of propofol-remifentanil total intravenous anesthesia ( TIVA) and sevoflurane volatile induction and maintenance anesthesia ( VIMA) for patients undergoing resection of benign breast mass. Methods 46 patients undergoing resection of benign breast mass were allocated randomly to receive propofol-remifentanil TIVA ( Group A) or sevoflurane VIMA ( Group B) . Respiratory rate ( RR) , heart rate ( HR) , and mean blood pressure ( MBP) were compared during procedure. Induction time, emergence time, and the incidence of adverse events were compared. Results Emergence time in Group A was significantly shorter than that in Group B. Respiratory rate and heart rate were significantly lower in Group A than in Group B. The incidence rates of hradypnea, bradycardia, and hypotension in Group A were significantly higher than those in Group B, and the incidence of excitement in Group A was lower than Group B.Conclusion Compared with sevoflurane VIMA , propofol-remifentanil TIVA provides faster emergence time, lower respiratory rateand heart rate, and lower incidence of emergence agitation.%目的 本研究予良性乳腺包块切除术患者应用保留自主呼吸的喉罩全身麻醉,分别全程给予瑞芬太尼-丙泊酚全凭静脉麻醉(TIVA)或七氟醚全凭吸入麻醉(VIMA),探讨两种麻醉方法的临床应用.方法 46例拟行良性乳腺包块切除术的患者随机分为TIVA组(A组)和VIMA组(B组),比较两组患者麻醉诱导速度,呼吸频率、心率、血压的改变.以及不良反应的发生率等指标.结果 A组患者苏醒时间明显短于B组.A组患者呼吸频率和心率明显低于B组.A组患者术中呼吸过缓、心动过缓、以及低血压等不良反应较B组发生率高,术后烦躁发生率较B组低.结论 瑞芬太尼-丙泊酚TIVA较七氟醚VIMA的苏醒更快,伴有较低的呼吸频率和心率,术后烦躁发生率较低.
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