临床药师对基层医院抗菌药物使用率、使用强度的影响

摘要

目的：了解临床药师对基层医院抗菌药物使用情况的影响。方法查阅基层医院临床药师参与制定抗菌药物给药方案前后出院病历643例,分析基本用药情况,计算抗菌药物使用率,并以限定日剂量( DDD)为单位计算使用强度(AUD)。结果临床药师参与前该基层医院抗菌药物使用率均在90%以上,AUD一般>85DDD,参与后抗菌药物使用率均可以降到60%以下,AUD一般在40DDD左右。结论临床药师参与抗菌药物给药方案,能有效地降低抗菌药物的使用率、使用强度。%Objective To understand the influence of clinical pharmacists on the use of antibiotics in basic hospital. Methods Consult a total of 643 cases of hospital medical records where clinical pharmacists whether participate in the formulation of the therapeutic regimen or not; analyze the use of antibiotics; calculate the antibiotic use rate and the antibiotic use density ( AUD) in defined daily doses ( DDD) . Results Antibiotic use rates of the basic hospital were all above 90% and AUD were generally higher than 85DDD, while the antibiotic use rate could decrease down to less than 60% and AUD were approximately 40DDD after clinical pharmacists participating in formulating therapeutic regimen. Conclusion By means of clinical pharmacists participating in the formulation of the therapeutic regimen, antibiotic use rate and use intensity can be reduced efficiently.