临床药师对降低心血管介入抗菌药物预防使用率的干预作用

摘要

Objective:To explore the antibacterial chemoprophylaxis usage for cardiovascular intervention reduced by Clinical pharmacist's intervention.Methods:Compared the rates of antibacterial chemoprophylaxis usage and postoperative infection for coronary angiography(CAG) and percutaneous coronary intervention(PCI) before and after the clinical pharmacist’s intervention.Results:After the four stages of intervention, the rates of antibacterial chemoprophylaxis usage for CAG and PCI decreased from 86.1%to 0%and 88.3%to 1.5%. There were significant differences (P<0.05);Before and after the pharmacist’s intervention, the postoperative infection rates were 0%.There was no significant difference(P=1). Conclusion:The clinical pharmacist's intervention played an important role in reducing the antibacterial chemoprophylaxis usage for cardiovascular intervention. They supervised pharmacy to promote the rational usage of antimicrobial agents.%　　目的：探讨临床药师对降低心血管介入抗菌药物预防使用率的干预作用。方法：对比临床药师干预前后我院冠状动脉造影术(CAG)和冠状动脉内支架术(PCI)抗菌药物预防使用率和术后感染情况。结果：通过4个阶段的干预,CAG和PCI抗菌药物预防使用率分别由干预前的86.1%和88.3%下降为0%和1.5%,均有显著差异(P<0.05)；干预前后术后感染率均为0%,无统计学差异(P=1)。结论：临床药师干预对降低心血管介入抗菌药物预防使用率效果显著,充分发挥了药学监督作用,促进了抗菌药物的合理使用。