纳米活性炭示踪技术在直肠癌根治术中的应用价值

摘要

目的 探讨纳米活性炭示踪技术在直肠癌根治术中的临床应用价值.方法 43例直肠癌患者随机分为纳米炭组20例和对照组23例,比较两组检获的淋巴结数、黑染淋巴结数及病理证实淋巴结癌转移情况.结果 两组共检获淋巴结670枚,纳米炭组(20.40 ±7.61)枚/例；显著高于对照组的(11.39 ±5.32)枚/例,P＜0.01.纳米炭组检获黑染淋巴结302枚中,癌转移淋巴结40枚；未黑染淋巴结106枚中,癌转移淋巴结6枚.对照组检获262枚淋巴结中,癌转移淋巴结26枚.黑染的淋巴结中癌转移率更高(P＜0.05).结论 在直肠癌根治术中采用纳米活性炭示踪技术可提高直肠癌根治术患者淋巴结检获数量和直肠癌病理分期的准确性,对直肠癌淋巴结清扫有一定指导作用.%Objective To investigate the clinical application value of nano carbon tracer technology in colorectal cancer radical mastectomy. Methods A total of 43 patients with colorectal cancer were randomly divided into nanometer carbon group of 20 cases and control group of 23 cases to compare seized lymph node number, black dye lymph node number and pathology confirmed carcinoma metastasis lymph node situation. Results There were 670 pieces of lymph node seized in two groups toally, including (20. 4 ± 7. 61) medals/case in nano carbon group and (11. 39 ± 5. 32) medals/case in control group. Lymph node number in nano carbon group was more than control group (P<0.05). In nano carbon group, the number of black dye lymph node was 302 including 40 pieces of cancer metastasis lymph node, while the non-black dye lymph node was 106 including 6 pieces of cancer metastasis lymph node. There was 26 pieces of cancer metastasis lymph node seized in all 262 pieces of lymph nodes in control group. The metastasis rate of black dye lymph node was higher ( P < 0. 05 ) . Conclusions The usage of nano carbon tracer can improve the number of lymph node in colorectal cancer radical mastctomy to ensure the accuracy of pathological stage and to be instructive for operation.