目的：比较3．0 T磁共振（MRI）动态增强与64层螺旋CT（64-MDCT）多期扫描对肝硬化背景下小肝癌的诊断价值。方法选择肝硬化合并小肝癌患者55例（66个癌性小结节），分别进行3．0 T MRI动态增强与64-MDCT多期扫描，由两位专家对检查结果进行判定，比较两种检查方法的诊断价值。结果两位观察者通过3．0 T MRI动态增强得到的ROC曲线下面积（AUC）分别为0．893±0．013、0．859±0．027，通过64-MDCT得到的AUC分别为0．657±0．034、0．679±0．026；两位观察者对两种检查方法的诊断价值比较，P均＜0．01。两位观察者采用3．0 T MRI动态增强诊断肝硬化背景下小肝癌的敏感度、特异度、阴性预测值均高于64-MDCT，P均＜0．01。结论3．0 T MRI动态增强对肝硬化背景下小肝癌的诊断价值高于64-MDCT。%Objective To evaluate the diagnostic performance of contrast-enhanced 3.0 T magnetic resonance imaging (MRI) and 64-multirow detector CT (64-MDCT) for small hepatocellular carcinoma (HCC) in patients with liver cirrho-sis.Methods Fifty-five cirrhotic patients with small HCCs (66 cancerous nodules ) were admitted to our hospital .All le-sions were quantitatively detected by contrast-enhanced 3.0 T MRI and 64-MDCT scanning.Two observers independently and randomly reviewed the 3.0 T MRI and 64-MDCT images on a lesion-by-lesion basis for the comparison of diagnostic value of the two methods.Results For each observer, the areas under the ROC curve were 0.893 ±0.013 and 0.859 ± 0.027 for 3.0 T MRI, respectively, as opposed to 0.657 ±0.034 and 0.679 ±0.026 for 64-MDCT, respectively.The differences between the two techniques were statistically significant for each observer (all P<0.01).The sensitivity, spe-cificity and negative predictive value of 3.0 T MRI for both observers were significantly higher than those of 64-MDCT ( all P<0.01).Conclusion The contrast-enhanced 3.0 T MRI shows a better diagnostic performance than that of 64-MDCT for the detection of small HCCs in patients with chronic liver disease .
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