糖尿病足合并感染患者血清高敏C反应蛋白和纤维蛋白原浓度变化及其相关性研究

摘要

Objective:To investigate the levels of fibrinogen(Fib) , high sensitivity C-reactive protein (hs-CRP) in subjects with type 2 diabetic patients with foot infection and the correlation between these two facts. Methods: The levels of Fib, hs-CRP were measured in 21 subjects with type 2 diabetic patients with foot infection ,19 subjects with type 2 diabetic patients foot ulcer and without infection, and 30 diabetic patients without foot ulcer. Results:The levels of Fib,hs-CRP in patients with type 2 diabetic patients with foot infection were higher than the patients with type 2 diabetic patients foot ulcer without infection and diabetic patients without foot ulcer and had sig-nificance(P<0. 01) .and there were relative among Fib and hs-CRP(P<0. 05). Conclusion: The levels of Fib , hs-CRP are higher in patients with type 2 diabetic patients with foot infection and have significant relative.%目的:探讨糖尿病足合并感染患者(DFI)血清高敏C反应蛋白(hs-CRP)及纤维蛋白原(Fib)水平变化及其相关性.方法:40例糖尿病足患者分为合并感染组21例和无合并感染组(DF) 19例,测定两项指标水平,并与30例糖尿病无合并足病组(DM)作对照.结果:DFI组hsC-RP和Fib水平显著高于DF组和单纯DM组(P＜0.01),且DF组显著高于单纯DM组,hsC-RP和Fib水平之间呈显著正相关(P＜0.01).结论:糖尿病足患者hsC-RP和Fib水平升高,感染后明显升高且显著相关.