临床结局不良的格林巴利综合征的早期识别

摘要

Objective:The efficacy and outcomes of standard treatment of Guillain‐Barre syndrome was diverse .It was more important to give a targeted individual treatment early .Therefore ,to determine the effect of standard treatment and outcome in early stage was very important .Methods:513 cases of GBS patients derived from the application mEGOS evaluation system for the first four weeks ,three months and six months after admitted to hospital for assessment ,application factors associated with poor outcome regression analysis verified .Results :Multivariate analysis showed that age ,preceding diarrhea and low MRC score on ad‐mission and 7 days after admission in the first four weeks with the patient ,3 months and 6 months of adverse outcomes associated with .Conclusion :mEGOS evaluation system can determine a more accurate early GBS patients six months after the onset of clinical outcomes ,but also early identification of those patients with poor outcome after standard treatment ,and give them more effective treatment programs in the future .%目的：探讨格林巴利综合征（CGBS ）规范治疗的临床疗效和结局。方法：收集衍生组GBS病例150例，应用mEGOS评价体系对GBS患者入院后第4周，3个月和6个月的结局进行评定，应用回归分析验证与不良结局相关的影响因素。结果：多变量分析显示高龄，前驱腹泻症状和入院时及入院第7天低 M RC评分与患者在第4周，3个月和6个月时的不良结局相关。结论：mEGOS评价体系能够在早期较为准确的判定GBS患者在发病半年后的临床结局，还能够早期识别那些规范治疗后结局较差的患者，以期在未来可以针对他们给予更有效的治疗方案。