平均血小板体积检测在评估ST段抬高型心肌梗死合并急性肾损伤风险中的意义

摘要

目的:探讨平均血小板体积(MPV)在评估ST段抬高型心肌梗死(STEMI)合并急性肾损伤(AKI)风险中的意义.方法:将222例STEMI患者按照入院时MPV水平分为MPV增高组(80例)及MPV正常组(140例),记录两组入院后一般临床资料以及住院期间 AKI发生情况,利用Logis-tic回归方程评价MPV在预测AKI发生中的风险.结果:MPV增高组Killip分级、冠脉梗死支数、血清BNP、Scr、cTnI 均高于MPV正常组(P<0.05),而eGFR、LVEF低于MPV正常组(P<0.05);MPV增高组AKI发生率高于MPV正常组(P<0.05);Logistic回归分析亦显示:MPV是STEMI合并AKI的独立危险因素.结论:MPV水平增高可能是STEMI合并AKI的独立危险因素,且有一定的风险预测价值,临床应当密切监测MPV水平的变化,以早期评估患者的预后.%Objective:To investigate the significance of MPV in assessing the risk of AKI in STEMI.Meth-ods:222 patients with STEMI were divided into Increased MPV group(n=80)and normal MPV group(n=140)ac-cording to MPV on admission.General clinical data of two groups occurrence of AKI during hospitalization were re-corded.Results:Killip score,coronary infarction count,serum BNP,Scr and cTnI of increased MPV group were higher than those of normal MPV group,the differences were statistically significant(P<0.05);incidence rate of AKI in increased MPV group was higher than normal group.Logistic regression analysis showed that MPV was in-dependent risk factor of AKI.Conclusion:increased M PV level may be an independent risk factor for AKI,and have some predictive value.Clinical monitoring of M PV should be closely monitored to assess the prognosis of patients at an early stage.