骶髂关节小针刀治疗强直性脊柱炎临床观察

摘要

目的：探讨骶髂关节小针刀治疗活动期强直性脊柱炎的疗效。方法：将90例活动期强直性脊柱炎患者随机分为治疗组和对照组，每组45例。治疗组采用常规药物口服联合骶髂关节针刀松解术治疗，对照组仅采用常规药物口服。2组1个疗程均为24周。采用脊柱痛评分、夜间痛评分、Bath强直性脊柱炎功能指数（BASFI）、Bath强直性脊柱炎病情活动指数（BASDAI）、Bath强直性脊柱炎测量学指数（BASMI）、C-反应蛋白、红细胞沉降率等指标综合评价骶髂关节小针刀治疗强直性脊柱炎的临床疗效。结果：治疗1周后，骶髂关节小针刀治疗组患者的脊柱痛评分、夜间痛评分和BASDAI、BASFI、BASMI明显低于对照组（P <0.05）；治疗24周后与对照组比较，脊柱痛评分、夜间痛评分和BASFI差异有统计学意义（P <0.05），BASDAI、BASMI差异无统计学意义（P >0.05）。在治疗过程中，2组C-反应蛋白、红细胞沉降率较治疗前均有明显下降，但两者同期比较，差异无统计学意义（P >0.05）。治疗组疗效显著优于对照组（P <0.05）。2组不良反应比较，差异无统计学意义（P >0.05）。结论：骶髂关节小针刀治疗强直性脊柱炎有一定效果，可在短期内显著缓解强直性脊柱炎症状。%Objective:To investigate the curative effect of sacroiliac joint acupotomy in the treatment of ankylosing spondylitis.Methods:90 patients with active ankylosing spondylitis were randomly divided into a treatment group and a control group,60 cases in each.The treatment group was treated by routine drug therapy combined with sacroiliac joint acupotomy,while the control group was only given routine drug treatment.The course of treatment for the two groups was 24 weeks.The spinal pain scores,night pain score,BASFI,BASDAI,BASMI,C-reactive protein and erythrocyte sedimentation rate etc.were used comprehensively evaluate the curative effect of sacroiliac joint acupotomy in the treatment of ankylosing spondylitis.Results:After a week of treatment,the spinal pain scores,night pain score,BASFI,BASDAI and BASMI of the treatment group were signiifcantly lower than those of the control group (P< 0.05);after 24 weeks of treatment,the differences of the spinal pain scores,night pain score and BASFI between the two groups had statistical signiifcance(P< 0.05),while the differences of BASDAI and BASMI had no statistical signiifcance(P> 0.05).In the process of treatment,C- reactive protein and erythrocyte sedimentation rate of the two groups were signiifcantly decreased than those before treatment,but there was no signiifcant difference between them during the corresponding period(P> 0.05).The curative effect of the treatment group was signiifcantly higher (P< 0.05). There was no signiifcant difference in adverse reactions between the two groups(P> 0.05).Conclusion:Sacroiliac joint acupotomy has a certain effect in the treatment of ankylosis spondylitis,which can significantly relieve the symptoms of ankylosing spondylitis in the short term.