经阴道彩色多普勒超声结合 CA125检测在卵巢良恶性肿瘤诊断中的价值

摘要

Objective To investigate the applicative value of transvaginal color doppler sonography com-bined with CA125 which is tumor detection maker in the the diagnosis of ovarian of benign and malignant tumor . Methods We analyzed sonographic features ,blood flow of transvaginal color doppler sonography and serum CA 125 level in 102 ovarian tumor cases and compared with pathological findings and study the sensitivity ,specificity and accuracy of diagnosis.Results The sensitivity,specificity and accuracy of the diagnosis of ovarian of benign and malignant tumor detected by transvaginal color doppler sonography were respectively 80.6%,95.8%and 91.2%. The sensitivity ,specificity and accuracy of the diagnosis of ovarian of benign and malignant tumor detected by tumor makers CA125 were 87.1%,87.3%and 87.3%respectively.The sensitivity,specificity and accuracy of the diag-nosis of ovarian of benign and malignant detected by transvaginal color doppler sonography combined with tumor makers CA125 were 93.5%,97.2%and 96.1%respectively.The sensitivity,specificity and accuracy of results de-tected by the combination of both methods were higher than the single one .Conclusion The combination among the sonographic features ,blood flow of transvaginal color doppler sonography and serum tumor markers CA 125 im-proves the efficiency of ovarian benign and malignant tumor diagnosis ,and therefore shows the great clinical value .%目的：探讨经阴道彩色多普勒结合肿瘤标志物CA125检测在卵巢良、恶性肿瘤诊断中的应用价值。方法回顾性分析102例卵巢肿瘤的阴道彩色多普勒超声声像图特征、血流情况及血清CA125水平，并与病理结果对照，对其诊断的灵敏度、特异度、准确度进行分析。结果经阴道彩色多普勒超声诊断卵巢良、恶性肿瘤的灵敏度、特异度、准确度分别为80．6％、95．8％、91．2％；经肿瘤标志物CA125诊断卵巢良、恶性肿瘤的灵敏度、特异度、准确度分别为87．1％、87．3％、87．3％；经阴道彩色多普勒超声结合肿瘤标志物CA125诊断卵巢良、恶性肿瘤的灵敏度、特异度、准确度分别为93．5％、97．2％、96．1％。两种方法结合诊断卵巢良、恶性肿瘤的灵敏度、特异度、准确度显著高于二者单独诊断。结论经阴道彩色多普勒超声检查卵巢肿瘤声像图特征、血流情况与血清肿瘤标志物CA125的结合检测提高了对卵巢肿瘤良、恶性诊断效能，具有较大的临床应用价值。