Objective To investigate the value of diffusion-weighted magnetic resonance imaging in the diagnosis and treatment of lung cancer. Methods 180 patients with lung cancer were retrospectively analyzed by routine diffusion weighted magnetic resonance imaging diagnostic techniques, and the application effect of diffusion weighted magnetic resonance imaging in the diagnosis and treatment evaluation of lung cancer was observed. Results The apparent diffusivity of non-small cell carcinoma and small cell carcinoma had obvious statistical difference. Further observation showed that the apparent diffusion coefficient of adenocarcinoma, squamous cell carcinoma and small cell carcinoma in non-small cell carcinoma also had obvious statistics ROC analysis of the apparent diffusion coefficient used to distinguish non-small cell carcinoma and small cell carcinoma area under the curve was 0. 748; apparent diffusion coefficient combined with serum tumor markers to diagnose lung cancer area was significantly greater than the apparent apparent diffusion coefficient or Serum tumor markers diagnosis; Pearson correlation analysis of apparent diffusion coefficient and lung cancer Ki-67 relationship value γ = - 0. 406; CT and diffusion-weighted magnetic resonance imaging were measured after treatment, the maximum diameter of tumor was significantly less than before treatment,However, there was no significant difference in the maximum diameter of tumor measured before and after treatment between CT and DWI. The relationship between the apparent diffusion coefficient of Pearson correlation analysis and the change rate of maximum diameter of lung cancer by CT was γ = - 0. 431. Conclusion Diffusion-weighted magnetic resonance imaging can accurately determine the pathological types and proliferation of lung cancer. Combined detection of serum tumor markers can further improve the diagnosis of lung cancer histopathology. Diffusion-weighted magnetic resonance imaging can be used to evaluate Treatment of lung cancer patients with high clinical value.%目的 探讨弥散加权磁共振成像技术在肺癌诊断及治疗效果评估中的应用价值.方法 对180例行弥散加权磁共振成像技术诊断的肺癌患者进行回顾性分析,观察弥散加权磁共振成像技术在肺癌诊断及治疗效果评估中的应用效果.结果 非小细胞肺癌与小细胞肺癌的表观扩散系数存在明显的统计学差异,进一步观察发现非小细胞肺癌中腺癌及鳞癌与小细胞肺癌的表观扩散系数同样存在明显的统计学差异,ROC分析出表观扩散系数用于区分非小细胞肺癌与小细胞肺癌的曲线下面积为0.748; 表观扩散系数联合相关血清肿瘤标志物诊断肺癌曲线下面积明显大于单一表观扩散系数或血清肿瘤标志物诊断; Pearson相关分析表观扩散系数与肺癌Ki-67的关系值γ = -0.406; CT与弥散加权磁共振成像技术均在治疗后测得的肿瘤最大径总和明显小于治疗前,但CT与弥散加权磁共振成像技术分别在治疗前后测得的肿瘤最大径总和差异不明显,Pearson相关分析表观扩散系数与CT评估肺癌最大径的变化率之间的关系值γ = -0.431.结论 弥散加权磁共振成像技术可对肺癌的病理类型及增殖程度进行准确判断,且联合相关血清肿瘤标志物检测可进一步提高对肺癌组织病理的诊断效果,同时弥散加权磁共振成像技术可用于评估肺癌患者治疗效果,具有较高的临床应用价值.
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