目的 比较经尿道前列腺等离子切除术与钬激光剜除术治疗良性前列腺增生的疗效与安全性.方法 选择2014年2月至2015年2月期间收治的80例良性前列腺增生病人,按照随机数字表法分为试验组和对照组.对照组采用经尿道前列腺等离子切除术治疗,试验组采用钬激光前列腺剜除术治疗,比较2组病人治疗效果及安全性 结果 试验组膀胱冲洗时间、出血量及住院时间均显著低于对照组(P≤0.05或P≤0.01),术中冲洗量显著高于对照组(P≤0.05);术前2组病人的国际前列腺症状评分(international prostate symptom score,IPSS)、生活质量评分(quality of life,QOL)、最大尿流率(Qmax)差异无统计学意义(P＞0.05).术后1月、3月及6月,2组IPSS与QOL评分及Qmax均较术前显著改善(P≤0.01),2组间比较差异无统计学意义(P＞0.05)试验组并发症发生率为7.50％,显著低于对照组(30.0％)(P≤0.01). 结论 经尿道前列腺钬激光剜除术治疗良性前列腺增生,能够显著降低膀胱冲洗时间、出血量及住院时间,不良反应发生率低,可在临床推广应用.%Objective To explore the efficacy and safety of transurethral plasma resection of prostate (TURP) and holmium laser enucleation of prostate (HoLEP) for benign prostatic hyperplasia (BPH).Methods Eighty cases of BPH were treated in our hospital from February 2014 to February 2015.The patients were divided into experimental group and control group randomly.Control group was treated by TURP,and experimental group was treated by HoLEP.The efficacy and safety were compared between two groups.Results The levels of bladder irrigation time,bleeding volume and hospitalization time were significantly lower in experimental group than those in control group (P≤0.05 or P≤0.01),and the amount of irrigation was significantly higher than that in control group (P≤ 0.05).Before operation,there were no significant difference in international prostate symptom score (IPSS),quality of life score (QOL),maximum urinary flow rate (Qmax) between two groups (P＞0.05);1 month,3 months and 6 months after operation,the scores of IPSS,QOL and Qmax were all significantly improved in two groups (P≤0.05).There was no difference in the two groups after operation (P＞0.05).The complication rate in the experimental group was 7.50％,compared with 30.0％ in the control group,(P≤0.01).Conclusions HoLEP treatment for patients with BPH can significantly reduce the bladder irrigation time,bleeding volume and hospitalization time,with high security.
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