Compounds isolated from Triglochin maritimum L. and composition for preventing, improving or treating benign prostatic hyperplasia comprising the same as an effective ingredient

摘要

The present invention relates to a compound for inhibiting the expression of 5AR (5α-reductase) derived from a branch, including the following compound 1, etc. isolated from the branch (Triglochin maritimum L.). Thereby, finasteride or dutasteride can be replaced, extracted from naturally derived components, and effectively treat prostatic hyperplasia by inhibiting the expression of 5AR1 and/or 5AR2 in PC3 cells of the prostate. have. [Compound 1]