Objective To investigate the anti-fatigue and improving immune function effects of Astragalus pollen powder, and to compare the effect with that of decoction pieces of Astragalus. Methods The SPF KM mice were used. The effects on improving immune function of Astragalus pollen powder at different dosages were detected by the carbon clearance method. The mice immune organs weight,and the anti-fatigue effects of Astragalus pollen powder at different dosages were also observed by the burden swimming test. Results The Astragalus pollen powder could rise the macrophage cytophagic index and coefficient of mice,increase the immune organ weights,and extend the mice burden swimming time. Conclusion The Astragalus pollen powder could enhance the immune function and exhibit an anti-fatigue effect. The Astragalus pollen powder at a low dosage could achieve same effect with decoction pieces of Astragalus at a large dose.%目的 观察黄芪破壁粉粒对小鼠免疫调节的作用和抗疲劳的作用,并与黄芪饮片进行比较.方法 取SPF 级 KM 种小鼠,采用炭粒廓清法、免疫器官质量法测定不同剂量黄芪破壁粉粒的免疫指标;采用小鼠负重游泳实验观察不同剂量黄芪破壁粉粒的抗疲劳作用.结果 黄芪破壁粉粒能够增加小鼠吞噬指数、吞噬系数及显著提高小鼠免疫器官指数;并能延长小鼠负重游泳时间.结论 黄芪破壁粉粒具有增强小鼠免疫及抗疲劳的作用.与黄芪饮片比较,黄芪破壁粉粒较低剂量即可达到大剂量黄芪饮片的效果.
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